Eiro Pharmacist

A Science Based View Of Eiro Research From An Eiro Independent Associate

EGCG and Leptin – The Weight Loss Hormone

copy-of-energycan2Leptin is a hormone made by fat cells that regulates food intake and energy expenditure.  Leptin communicates between fat cells and the brain.  Leptin’s messages:  Stop eating/burn fat, or Eat more/store fat.  Years ago scientist thought that if you lowered Leptin levels you would increase appetite and increase fat storage.  We now know that just the opposite is true, lower Leptin levels decrease appetite and increase fat metabolism.  There is clear evidence that green tea’s polyphenols (EGCG) are a factor in depressing Leptin levels as well as affecting other hormone levels important in regulating appetite.  There is evidence that EGCG of green tea holds promise in many areas of weight loss.  Besides affecting Leptin levels, green tea also increases noradrenaline levels.  Noradrenaline is a neurotransmitter within the brain that plays a major role in activation of brown fat tissue.  Brown adipose (fat) tissue is the only metabolically active fat in the body.  Activation of brown fat by increased noradrenaline levels is significant because it predominately burns calories from the white fat located around our waistline, hips and thighs.  If you remember from the post on Guarana, the Xanthines found in Eiro Energy create a feeling of fullness and also increase fat metabolism and work synergistically with the EGCG also found in Eiro Energy to increase daytime thermogenesis ( the body’s own rate of burning calories) by 35-43%.(1)*  So, in summary, there is scientific evidence that the EGCG found in Eiro Energy can lower Leptin levels and increase Noradrenline levels, which can decrease your appetite and increase your fat burning ability.  Combine this with the Xanthines found in Guarana and Eiro Energy could make and excellent weight loss product.*

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References:

1.  Dulloo AG, Duret C, Rohrer D, et al. Efficacy of a green tea extract rich in catechin ployphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans.  A J Clin Nutr 1999;70:1040-5.